Lynch syndrome is a inherited disease which is caused due to the sport in the DNA furbish up gene . Thus , any mistake in the familial information of DNA is not corrected , resulting in the increased risk of malignant neoplastic disease . This is an autosomal rife cistron and perish on the next propagation without any skip . The chances for contract this disease in the next generation are 50:50 .
Screening And Surveillance : As the affected role with Lynch syndrome carries relatively high risk of various types of malignant neoplastic disease , particularly colorectal Crab , the screening and surveillance should be periodically done for these patients . There are two types of methods for screening the patients . These methods are Microsatellite imbalance test and the immunochemistry analysis . On the foundation of these screening tests , the Lynch syndrome is identify . Also , the screening methods should also be done to test for genus Cancer . The world-wide method acting used for screening is biopsy .
Diet : Diet also plays a major role in the bar of malignant neoplastic disease from Lynch syndrome . In the Lynch syndrome , due to mutation , the power of the cell to correct the mistakes in DNA is compromised and this result to higher chancer of malignant neoplastic disease . Thus , the dieting should be such that it does not conduct to the development of cancer . The diet may either should not contribute to malignant neoplastic disease or may reduce the hazard of malignant neoplastic disease development . High sugar and high-pitched fat diet increase the peril of ontogenesis of Crab . Thus , these ingredient should be avoided . Further , sealed fixings such as antioxidant including coenzyme Q10 , resveratrol , green tea extract should be incorporate in the dieting .
Surgical Management : cautionary surgery is done in affected role who have the high peril of development of cancer . Colectomy , hysterectomy and bilateral salpingo - oophorectomy are the types of operation used for this purpose .
Prevention Through Drugs : The risk of cancer growth from Lynch syndrome may also be reduced with the assist of certain drugs . It has been establish through studies that Empirin bring down the risk of Crab in patient with Lynch syndrome . Further , some inquiry conclude that the administration of oral preventive reduces the risk of development of endometrial cancer .
Lifestyle : The risk of cancer due to Lynch syndrome can also be reduced through a argus-eyed lifestyle . The patient should maintain a tidy body weight and fend off imbibing and smoking . Further , the patient should nullify spicy food and do exert daily . Also , the patient should whole remove the processed essence from his dieting .
Genetic Testing : genetical testing is sometimes done for the family fellow member of the of late diagnosed cancer due to Lynch syndrome . This testing will help in strategizing the aesculapian attention and follow - up scrutiny .
Annual Examination : mostly non - invasive scrutiny such as pelvic interrogatory is done once in a year to corroborate the presence or absence of any case of tumor in high risk patients .
There is no room to slim down the risk of Lynch syndrome as the disease is genetically related . However , there are methods to slim down the risk of development of malignant neoplastic disease . This can be done through right screening and examination . Proper genetical testing methods should be used for truth of result . operative methods are also used for reduction in the risk of exposure of cancer . dieting and life style also trifle a major role in lour the risk of Crab .